Researchers have discovered why long-term use of L-DOPA (levodopa), the most effective treatment for Parkinson's disease, commonly leads to a movement problem called dyskinesia, a side effect that can be as debilitating as ...
Sep 10, 2015
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The death of brain cells in Parkinson's disease may be caused by a form of cellular energy crisis in neurons that require unusually high quantities of energy to carry out their job of regulating movement, researchers at the ...
Aug 27, 2015
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Stimulation of a certain population of neurons within the brain can alter the learning process, according to a team of neuroscientists and neurosurgeons at the University of Pennsylvania. A report in the Journal of Neuroscience ...
May 13, 2014
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(Medical Xpress)—Neurodegenerative diseases like Parkinson's disease involve the death of thousands of neurons in the brain. Nerve growth factors produced by the body, such as GDNF, promote the survival of the neurons; ...
Jan 30, 2014
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The earliest signs of Parkinson's disease can be deceptively mild. The first thing that movie star Michael J. Fox noticed was twitching of the little finger of his left hand. For years, he made light of the apparently harmless ...
Apr 23, 2013
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The key hallmark of Parkinson's disease is a slowdown of movement caused by a cutoff in the supply of dopamine to the brain region responsible for coordinating movement. While scientists have understood this general process ...
Mar 13, 2013
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Parkinson's disease, the second most common type of progressive dementia after Alzheimer's disease, affects nearly 1 million people in the U.S. and an estimated 10 million individuals worldwide. Each year, close to 90,000 ...
Feb 23, 2024
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Through transcriptomic profiling of more than 300,000 cells in human substantia nigra, a part of the brain that helps control the body's movements, a research team has identified a previously unreported neuron type with vulnerability ...
Jan 12, 2024
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You have spent the past few days on a cloud over your forthcoming, well-deserved holidays, and will go back to daydreaming about them as soon as you finish this article. And the truth is that the benefits of a good holiday ...
Jul 13, 2023
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Brain imaging scans are powerful tools for diagnosing Parkinson's disease (PD) and ruling out other motor disorders. In PD, the presence of α-synuclein (α-Syn) in Lewy bodies and Lewy neurites in the brain, particularly ...
Jul 10, 2023
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