Genetic switch turns tumor suppressor into oncogene in colorectal cancer
Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide, and only around 10% of patients survive for five years after being diagnosed.
Sep 11, 2023
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Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide, and only around 10% of patients survive for five years after being diagnosed.
Sep 11, 2023
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A protein famed among scientists and clinicians for its ability to suppress the development of many types of tumors may just be moonlighting as a cancer fighter, a recent study by researchers at Stanford Medicine found. The ...
Aug 9, 2023
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A University of Kentucky Markey Cancer Center research team identified an existing cancer drug that shows promise as a treatment for the most common type of non-small cell lung cancer.
Jul 19, 2023
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Healthy cells work hard to maintain the integrity of our DNA, but occasionally, a chromosome can get separated from the others and break apart during cell division. The tiny fragments of DNA then get reassembled in random ...
Jun 15, 2023
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Van Andel Institute scientists have pinpointed how a specific gene mutation triggers an inflammatory cascade that may drive development of treatment-resistant cancers.
May 11, 2023
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Researchers from Harvard's Stem Cell and Regenerative Biology (HSCRB)'s Zon lab have discovered a new mechanism that influences melanoma development, a finding that could have wide implications for patients across a variety ...
Apr 27, 2023
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Understanding how cancer develops is critical for designing effective, personalized cancer therapies. Researchers have known for years that cancer begins with mutations in certain types of genes. One of these types of cancer ...
Apr 6, 2023
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The number of immune cells in and around kidney tumors, the amount of dead cancer tissue, and mutations to a tumor suppressor gene called PBRM1 form a biomarker signature that can predict—before treatment begins—how well ...
Apr 6, 2023
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Human papillomavirus (HPV)-negative head and neck squamous cell carcinoma (HNSCC) and lung cancer can have disruptive mutations in TP53 and/or CDKN2A tumor suppressor genes, which are associated with poor patient survival.
Apr 5, 2023
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Two key proteins linked to cell division can reliably predict disease recurrence in prostate cancer after radiotherapy treatment, according to new research.
Apr 4, 2023
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