During carcinogenesis, malignant cells undergo uncontrolled division, causing tumor dissemination. Target therapy is an actively developing area of cancer treatment that includes blocking the action of certain proteins that ...
Aug 2, 2018
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Myeloid derived suppressor cells (MDSCs), produced in the bone marrow as part of the human immune response to a tumor, may have a potent immunoregulatory role following viral infection. The similarities and differences between ...
Jan 26, 2017
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The startling discovery that hundreds of thousands of Brazilians have a genetic mutation that undermines their ability to resist cancer is helping labs worldwide in their search for new treatments for the disease. Sue Armstrong ...
Sep 15, 2015
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Researchers at Genes and Cancer group at Bellvitge Biomedical Research Institute (IDIBELL), led by Montse Sanchez-Cespedes, have identified the PARD3 gene as a tumor suppressor that is inactivated in lung cancer squamous ...
Apr 14, 2015
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Direct targeting and induction of immunological attacks on cancer cells are two widely used approaches for the treatment of cancer. But Professor Hiromi Kumon and colleagues at Okayama University have developed a third and ...
Sep 30, 2014
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The Genes and Cancer Group at the Cancer Epigenetics and Biology Program of the IDIBELL has found that the MAX gene, which encodes a partner of the MYC oncogene, is genetically inactivated in small cell lung cancer. Reconstitution ...
Jan 9, 2014
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New study suggests that selective blockade of CRM1-dependent nuclear export represents a completely novel, tumour metastasis-selective approach for the treatment of advanced metastatic prostate cancers.
Nov 15, 2013
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Researchers from the Biological clues of the invasive and metastatic phenotype group of the Bellvitge Biomedical Research Institute (IDIBELL) led by Isabel Fabregat have discovered the relationship between the TGFb signalling ...
Nov 6, 2013
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Scientists from the National Cancer Centre Singapore (NCCS) have discovered the workings of the gene that has been hindering treatment response in cancer patients. This discovery was made after 5 years of studying the mutant ...
Jan 25, 2013
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Alterations in the formation of ribosomes (the elements of the cell where proteins are made) cause the induction of p53 protein and cell cycle disruption. This process is crucial to understand fundamental biological processes ...
May 22, 2012
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