About thirty percent of all medical drugs such as beta-blockers or antidepressants interact with certain types of cell surface proteins called G protein coupled receptors. In collaboration with researchers from the Paul Scherrer ...
Feb 3, 2016
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Nearly half of HIV infected patients suffer from impaired neurocognitive function. The HIV protein transactivator of transcription (Tat) is an important contributor to HIV neuropathogenesis because it is a potent neurotoxin ...
Jan 29, 2016
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The human brain is composed of complex circuits of neurons, cells that are specialized to transmit information via electrochemical signals. Like the circuits in a computer, these neuronal circuits must be connected in particular ...
Dec 17, 2015
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In the Age of Personalized Medicine, we've learned that one size doesn't fit all, least of all in cancer. Cancer is a disease of your cells, and sorting out your cancer from all others is a daunting challenge but one that ...
Dec 11, 2015
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Bottom Line: Resistance to CD19 CAR T-cell therapy, a type of immunotherapy that yields long-lasting remissions in many patients with B-cell leukemia, can be caused by CD19 splicing alterations, leading to loss of certain ...
Oct 29, 2015
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The proteins CD47 and SIRPα are fundamental to establishing a correct number of immune cells, so-called B lymphocytes. This according to a dissertation by Shrikant Shanital Kolan from Umeå University in Sweden.
Sep 22, 2015
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Researchers at the Virginia Bioinformatics Institute at Virginia Tech have uncovered key cellular functions that help regulate inflammation—a discovery that could have important implications for the treatment of allergies, ...
Aug 27, 2015
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The immune system must constantly adapt to its environment in order to protect a body effectively. The so-called T cells are an important example in this regard. One of their functions is to form the immune system's "memory". ...
Jun 12, 2015
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A*STAR researchers have shown that the RASAL2 gene, which is known to inhibit tumor growth in some breast cancers, actually advances tumor formation and metastasis in more aggressive forms of breast cancer and have suggested ...
May 27, 2015
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By comparing flu viruses to the virus that causes measles, researchers fine-tuned a tool that may enable faster vaccine design, according to a study led by Mount Sinai researchers and published online this week in the journal ...
May 21, 2015
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