Scientists from Tokyo Metropolitan University have realized a new polymer that can effectively transport plasmid DNA into T-cells during chimeric antigen receptor (CAR) T-cell therapy, a key treatment for blood cancer. Importantly, ...
Oct 2, 2023
0
12
According to new research in the journal Immunity, T cells have a nuclear receptor doing something very odd—but very important—to help them fight pathogens and destroy cancer cells. This receptor, called retinoic acid ...
Aug 18, 2023
0
68
Published online ahead of print in the journal Oncogene, a study led by Josep Villanueva, an Investigator at the Vall d'Hebron Institute of Oncology (VHIO), shows that the receptor for advanced glycation end-product (RAGE) ...
Aug 8, 2023
0
1
Researchers from the University of Colorado Anschutz Medical Campus have identified a potential new immune checkpoint receptor that could lead to treatments for diseases such as lung and bowel cancer and autoimmune conditions ...
Jun 30, 2023
0
66
Cachexia is a syndrome characterized by severe loss of weight and muscle mass. It is present in approximately half of all lung cancer patients and is particularly damaging in cases of non-small cell lung cancer. Early detection ...
May 10, 2023
0
9
The human body naturally produces opioid-like substances, such as endorphins, that block the perception of pain and increase the feeling of well-being. Similarly, opioid drugs, including morphine or fentanyl, are widely used ...
Apr 19, 2023
0
77
The enzyme TBK1 is an important component of the innate immune system that plays a critical role in the defense against viruses. Upon mutation-induced loss of TBK1 function, patients show an increased susceptibility to viral ...
Mar 10, 2023
0
24
Hitting two targets at the same time may be the key to stopping the spread of aggressive cancers, according to new research from the University of East Anglia and the Quadram Institute.
Dec 12, 2022
0
20
New research has revealed how the tau protein, a critical element in the formation of Alzheimer's disease, is also involved in normal learning processes in the healthy brain—potentially providing a focal point for future ...
Aug 23, 2022
0
22
Olfactory receptors, present on the surface of sensory neurons in the nasal cavity, recognize odorant molecules and relay this information to the brain. How do these neurons manage to detect a large variability of signals ...
May 30, 2022
0
51
