Schizophrenia may be associated with the excessive formation of oversized and hyperactive synaptic connections between nerves in the brain, a mouse model and a human post-mortem study published in Science Advances by RIKEN ...
Oct 3, 2023
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Researchers from the University of Tokyo reveal how the presynaptic Ube3a E3 ligase, a causal factor in Angelman syndrome, eliminates neural chatter. The study helps find a better drug target for the Angelman syndrome treatment.
Sep 14, 2023
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When you interact with the world around you, your experiences are recorded as changes in the connection strengths between neurons in your brain. This process, called synaptic plasticity, alters how information flows through ...
Jul 27, 2023
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Perhaps the most obvious feature of a neuron is the long branch called an axon that ventures far from the cell body to connect with other neurons or muscles. If that long, thin projection ever seems like it could be vulnerable, ...
Jun 12, 2023
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An often-overlooked communication strategy for neurons might be more prevalent than previously believed.
Jun 12, 2023
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Johns Hopkins scientists have developed a method involving artificial intelligence to visualize and track changes in the strength of synapses—the connection points through which nerve cells in the brain communicate—in ...
Jun 5, 2023
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Links have been reported between schizophrenia and proteins produced by the immune system that can act against one's own body, known as autoantibodies. In a study published in Brain Behavior and Immunity, Japanese researchers ...
May 31, 2023
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Scientists have long known that the cells' "protein destruction machine," the proteasome, plays a crucial role in protein clearance within the brain. However, a new study published in Science has revealed that its essential ...
May 25, 2023
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The mechanisms underlying the pathogenesis of epilepsy, a neurological disorder characterized by excessive electrical activity in the brain, remain unknown. Now, using a novel radiotracer ([11C]K-2, the first technology to ...
May 18, 2023
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Fresh insights into the spread of damaging proteins that build up in the brains of people with Alzheimer's disease could hold the key to stopping the condition from progressing, a study says.
May 15, 2023
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