Sufferers of Parkinson's disease have clumps of α-synuclein (alpha-synuclein), sometimes known as the "Parkinson's protein," found in the brain. These destroy cell membranes, eventually resulting in cell death. Now, a method ...
Jul 2, 2020
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Learning, memory and behavioral disorders can arise when the connections between neuron, called synapses, do not change properly in response to experience. Scientists have studied this "synaptic plasticity" for decades, but ...
Jun 30, 2020
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Neuroscientists at MIT's Picower Institute for Learning and Memory have found that a protein acts like a volume dial for the release of neurotransmitters, the chemicals that neurons release across connections called synapses ...
May 6, 2020
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Forty years since its discovery, much remains to be discovered about an enzyme called CaMKII that plays a key role in shaping learning and memory in the brain.
Feb 21, 2020
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Promoting the signaling pathway of reelin, an essential extracellular protein for the neuronal migration and synaptic plasticity, could be an effective therapeutic strategy to counterbalance the main cognitive, biochemical ...
Jan 23, 2020
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Chronobiologists at Ludwig-Maximilians-Universität (LMU) in Munich, Germany, show in two articles in the journal Science how critical the sleep-wake cycle is for protein and phosphorylation dynamics in synapses to ultimately ...
Oct 11, 2019
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Researchers from Utrecht University have clarified the function of proteins that play a role in signal transmission between neurons. Without these proteins, it is more difficult to pass on nerve stimuli, which may play a ...
Oct 9, 2019
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Researchers from the Institute of Neurosciences of the University of Barcelona (UBNeuro), Hospital Clínic and the August Pi i Sunyer Biomedical Research Institute (IDIBAPS) have identified a group of genetic variants related ...
Sep 27, 2019
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Our brains contain millions of synapses—the connections that transmit messages from neuron to neuron. Within these synapses are hundreds of different proteins, and dysfunction of these proteins can lead to conditions such ...
Sep 26, 2019
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A study published today in the journal Cell Reports sheds new light on how the CD2AP gene may enhance Alzheimer's disease susceptibility. Integrating experiments in fruit flies, mice and human brains, a multi-institutional ...
Aug 13, 2019
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