An injury pathway in the neurons of fruit flies may cause the loss of synapses in diseases such as Alzheimer's and ALS, according to University of Michigan researchers.
Oct 4, 2017
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Researchers have discovered that a protein called phosphorylated α-synuclein, which is associated with several neurodegenerative diseases such as Parkinson's disease and Lewy body dementia, is also involved in the normal ...
Jan 9, 2024
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A study published today in the journal Cell Reports sheds new light on how the CD2AP gene may enhance Alzheimer's disease susceptibility. Integrating experiments in fruit flies, mice and human brains, a multi-institutional ...
Aug 13, 2019
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Forty years since its discovery, much remains to be discovered about an enzyme called CaMKII that plays a key role in shaping learning and memory in the brain.
Feb 21, 2020
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UNC School of Medicine researchers have found for the first time a biochemical mechanism that could be a cause of "chemo brain" - the neurological side effects such as memory loss, confusion, difficulty thinking, and trouble ...
Dec 3, 2014
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Amyotrophic lateral sclerosis, or ALS, attacks nerve cells known as motor neurons in the brain and spinal cord, gradually leading to paralysis. The loss of function of an important gene, C9orf72, may affect communication ...
Jun 30, 2021
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Researchers at the Max Planck Florida Institute for Neuroscience have uncovered a critical molecule that regulates synaptic transmission.
Dec 2, 2015
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Korea Brain Research Institute (KBRI, Pann-Ghill Suh (President)) announced that Dr. Kea Joo Lee and Dr. You-Na Jang of the Neural Circuits Research Group have identified the mechanism causing synaptic loss in Alzheimer's ...
Feb 24, 2021
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Learning and memory are crucial aspects of everyday life. When we learn, our neurons use chemical and molecular signals to change their shapes and strengthen connections between neurons, a process known as synaptic plasticity. ...
Mar 9, 2017
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Promoting the signaling pathway of reelin, an essential extracellular protein for the neuronal migration and synaptic plasticity, could be an effective therapeutic strategy to counterbalance the main cognitive, biochemical ...
Jan 23, 2020
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