Although most neurotransmitters perform the same basic role, they are not fungible. Each takes the baton from an incoming action potential and passes the neural message across the synaptic divide, yet each flavor of transmitter ...
Promoting the signaling pathway of reelin, an essential extracellular protein for the neuronal migration and synaptic plasticity, could be an effective therapeutic strategy to counterbalance the main cognitive, biochemical ...
Jan 23, 2020
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Researchers at Chalmers University of Technology and Gothenburg University in Sweden have achieved something long thought almost impossible—counting the molecules of the neurotransmitter glutamate released when a signal ...
Jan 21, 2020
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New research by Dorothy P. Schafer, Ph.D., at the University of Massachusetts Medical School, reveals the molecular process in which synaptic connections in the brain are damaged in multiple sclerosis and how this contributes ...
Jan 21, 2020
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How do the physical parts of a neuron enable it to process and communicate information? Relating structure to function is a longstanding goal in neuroscience. In the latest issue of the journal Neuron, the group of Peter ...
Jan 9, 2020
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Though scientist Richard Semon introduced the concept of the "engram" 115 years ago to posit a neural basis for memory, direct evidence for engrams has only begun to accumulate recently as sophisticated technologies and methods ...
Jan 3, 2020
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Researchers examined the contribution of N-methyl-D-aspartate receptor subunits in the redox-mediated decline in NMDAR function during aging.
Oct 15, 2019
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Chronobiologists at Ludwig-Maximilians-Universität (LMU) in Munich, Germany, show in two articles in the journal Science how critical the sleep-wake cycle is for protein and phosphorylation dynamics in synapses to ultimately ...
Oct 11, 2019
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The ability to hear relies on neurons to constantly transmit information at very rapid timescales. This rapid rate of information transmission results in intense energetic demands. Within our cells, microscopic power plants ...
Oct 9, 2019
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Researchers from Utrecht University have clarified the function of proteins that play a role in signal transmission between neurons. Without these proteins, it is more difficult to pass on nerve stimuli, which may play a ...
Oct 9, 2019
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