It's a scientific riddle tangled up in a complex web. How do you turn an immune cold cancer into one that responds to immunotherapy?
Aug 2, 2021
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In a major advancement in the field of gene therapy for rare and devastating diseases, researchers at Children's Hospital of Philadelphia (CHOP) have developed a "dimmer switch" system that can control levels of proteins ...
Jul 28, 2021
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St. Jude Children's Research Hospital scientists and collaborators in Sweden and Japan are reporting that the enzyme NUDT15 plays a role in how patients respond to antiviral therapy with the common drugs ganciclovir and acyclovir. ...
Jul 8, 2021
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In cancer research, it's a common goal to find something about cancer cells—some sort of molecule—that drives their ability to survive, and determine if that molecule could be inhibited with a drug, halting tumor growth. ...
Jul 2, 2021
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Understanding cellular metabolism—how a cell uses energy—could be key to treating a wide array of diseases, including vascular diseases and cancer.
Jun 18, 2021
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A team of researchers at Innovative Molecules GmbH, working with several other institutions in Germany, has developed a small-molecule therapy for the treatment of latent herpes simplex virus infections. In their paper published ...
A personalized cancer vaccine developed with the help of a Mount Sinai computational platform raised no safety concerns and showed potential benefit in patients with different cancers, including lung and bladder, that have ...
Apr 11, 2021
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A dysfunctional immune system significantly contributes to the development of cancer. Several therapeutic strategies to activate the immune system to target cancer cells have been approved to treat different types of cancer, ...
Apr 8, 2021
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Radiation therapy appears to increase the expression of genes with mutations that induce an immune response to malignant cells, according to preclinical research by Weill Cornell Medicine and NewYork-Presbyterian investigators. ...
Mar 31, 2021
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An international research group led by the University of Basel has developed a promising strategy for therapeutic cancer vaccines. Using two different viruses as vehicles, they administered specific tumor components in experiments ...
Mar 3, 2021
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