A chimeric antigen receptor (CAR) T-cell therapy that targets the protein mesothelin showed no evidence of major toxicity and had antitumor activity in patients with malignant pleural disease from mesothelioma, according ...
Mar 31, 2019
0
1
An attractive approach to liver cancer treatment is to bolster the body's own immune defenses. Now an international team involving A*STAR researchers has genetically engineered human T cells to endow them with both specificity ...
Mar 18, 2019
0
70
Healthy white blood cells, called "T-cells," play a crucial role in how the body fights follicular lymphoma. That's according to the results of a study led by Mayo Clinic hematologists Zhi Zhang Yang, M.D., and Stephen Ansell, ...
Feb 20, 2019
0
60
Scientists at UW Medicine's Institute for Protein Design (IPD) in Seattle have created a new protein that mimics the action of a key immune regulatory protein, interleukin 2 (IL-2). IL-2 is a potent anticancer drug and ...
Jan 9, 2019
0
232
Cytomegalovirus is widespread and remains in the body for a lifetime after infection. In healthy individuals, this virus is usually kept in check, but can become dangerous when the immune system is weakened or during pregnancy. ...
Jan 9, 2019
0
2
University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a potential way to target a subtype of acute myeloid leukemia (AML) using chimeric antigen receptor (CAR) T-cell therapy, a form ...
Jan 4, 2019
0
2
Scientists at the University of Southampton have developed a new antibody that could hold the key to unlocking cancer's defence against the body's immune system.
Nov 14, 2018
0
38
In recent years, researchers have begun to fight cancer by genetically engineering a patient's own immune system to target the disease. Quad Technologies, a company that grew out of a Northeastern research lab, has been developing ...
Oct 18, 2018
0
0
In a study out this week in Science Translational Medicine, an international team led by researchers at Vanderbilt University Medical Center sheds new light on the cause of pulmonary fibrosis and demonstrates a way to impede ...
Oct 5, 2018
0
41
Women are more prone to the development of autoimmune diseases. The female hormone estrogen is likely to affect the immune system. A team of scientists from Turku Center for Biotechnology and University of Georgia reported ...
Jun 1, 2018
0
430
