New adoptive T cell therapies—in which T cells, the immune system's natural hunters patrolling the body for foreign adversaries, are retrieved from cancer-riddled patients, super-charged and amplified outside the body, ...
Feb 10, 2023
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CAR T-cell therapy, a certain kind of cancer treatment in which the immune system's T cells are programmed to attack tumor cells, is effective in mice with ovarian cancer, according to a study published in The Journal for ...
Feb 6, 2023
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A team of medical specialists working at Memorial Sloan Kettering Cancer Center in New York has found that donated white blood cells can be used effectively as part of CAR T cell therapy to treat myeloma patients.
There are many forms of autoimmune disease, but by definition they all have one thing in common—they arise when the body's immunological defenses go awry and attack our cells or trigger biochemical changes that lead to ...
Jan 25, 2023
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Inhibiting a particular protein in cancer-killing immune cells might improve the long-term effectiveness of CAR T-cell and other immune checkpoint therapies, according to a new study by researchers at The Ohio State University ...
Jan 24, 2023
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A combination of two next-generation immunotherapy drugs has shown promising clinical activity in treating patients with refractory metastatic colorectal cancer, a disease which has not previously responded well to immunotherapies, ...
Jan 23, 2023
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The recent years have seen a wave of adoptive cell therapies (ACTs), a type of immunotherapy in which T cells (T cell transfer therapy) and other immune cells are obtained from patients, activated and multiplied outside the ...
Jan 10, 2023
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A MedUni Vienna research team has discovered a highly potent biomarker for clinical response to CAR-T cell therapy, describing the prerequisites for optimal use of this novel therapy for lymphoma treatment. The current findings ...
Jan 9, 2023
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Teaching the body's immune cells to recognize and fight cancer is one of the holy grails in medicine. Over the past two decades, researchers have developed new immunotherapy drugs that stimulate a patient's immune cells to ...
Dec 16, 2022
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The Shin Kaneko laboratory at CiRA has developed a method to generate CAR-T cells from iPS cells (iCAR-T cells) that possess vastly improved anti-tumor activity in a mouse model of solid tumors.
Dec 13, 2022
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