New research has uncovered the previously unknown presence of CD19—a B cell molecule targeted by chimeric antigen receptor (CAR) T cell immunotherapy to treat leukemia, lymphoma, and multiple myeloma—in brain cells that ...
Sep 21, 2020
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Unlike other forms of blood cancer, acute myeloid leukemia (AML) cannot currently be treated with CAR-T cell immunotherapy. The reason is that specific molecular targets with which certain immune cells could specifically ...
Mar 13, 2023
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The memory of the human immune system is critical for the development of vaccines. Only if the body recognizes a pathogen with which it has already come into contact in the case of a second infection, the immune system can ...
Dec 24, 2012
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Chimeric antigen receptor (CAR) T cells can be remarkably effective in treating leukemias and lymphomas, but there are no successful immunotherapies for neuroendocrine tumors (NETs) and gastrointestinal cancers (GICs) yet. ...
Mar 24, 2022
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New research led by the University of Birmingham suggests that skin cancer patients could have a better prognosis if their T cells send messages from five specific genes in their immune response to drugs given to treat the ...
Sep 16, 2021
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By screening millions of molecular targets, researchers have uncovered a tumor beacon detected by the immune cells of two patients with colorectal cancer.
Dec 21, 2017
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Scientists from the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed a technique that will enable researchers to more efficiently isolate and identify rare T cells that are ...
Jan 12, 2021
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Henry Ford Cancer Institute has treated its first patient with CAR T-cell therapy, an approach that uses engineered cells from a patient's immune system to destroy cancer. The altered cells remain active for years after the ...
Jun 18, 2019
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A screening tool developed at the University of Strathclyde, U.K., could increase the number of tests on a solid tumor sample by up to 50 times.
Jun 21, 2022
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Targeting two brain tumor-associated proteins—rather than one—with CAR T cell therapy shows promise as a strategy for reducing solid tumor growth in patients with recurrent glioblastoma (GBM), an aggressive form of brain ...
Mar 13, 2024
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