A one-year follow-up study led by The University of Texas MD Anderson Cancer Center revealed a majority of patients with mantle cell lymphoma resistant to prior therapies may benefit from treatment with CD19-targeting chimeric ...
Dec 9, 2019
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Bioengineers at the University of California San Diego are a step closer to making CAR T-cell therapy safer, more precise and easy to control. They developed a system that allows them to select where and when CAR T cells ...
Oct 15, 2019
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Researchers at The University of Texas MD Anderson Cancer Center have discovered how an aggressive form of prostate cancer called double-negative prostate cancer (DNPC) metastasizes by evading the immune system. The investigators ...
Jul 18, 2019
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A team led by the Freiburg biologists Prof. Dr. Wolfgang Schamel and Prof. Dr. Wilfried Weber conducted an experiment in which they controlled the duration of the interaction of a specific protein with T cells, a type of ...
May 6, 2019
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Neuroblastoma is the most common extracranial solid cancer in children, and patients with high-risk disease are challenging to treat. In a promising development, researchers at Baylor College of Medicine released initial ...
May 2, 2019
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Renal fibrosis, the abnormal accumulation of fibrotic material within the kidney, hinders kidney function and may lead to eventual renal failure. Using genetically altered mice, researchers from Duke University investigated ...
Apr 16, 2019
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A new form of cancer immunotherapy has been given to a University of California, San Diego Health patient in the first test of immune cells grown from stem cells.
Apr 16, 2019
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Aire expression in the thymus contributes to immune tolerance by eliminating auto-reactive T cells; insufficient elimination causes autoimmune disorders. The Aire gene was thought to be expressed only in the thymus, but recently, ...
Apr 11, 2019
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A chimeric antigen receptor (CAR) T-cell therapy that targets the protein mesothelin showed no evidence of major toxicity and had antitumor activity in patients with malignant pleural disease from mesothelioma, according ...
Mar 31, 2019
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An attractive approach to liver cancer treatment is to bolster the body's own immune defenses. Now an international team involving A*STAR researchers has genetically engineered human T cells to endow them with both specificity ...
Mar 18, 2019
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