How do our muscles respond at the molecular level to exercise? Researchers at Helmholtz Munich and the German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE) have unraveled the cellular basis and signaling pathways ...
Sep 20, 2023
0
45
Researchers at Massachusetts General Hospital (MGH) have discovered that the interferon gamma receptor (IFNgR) signaling pathway is critical for susceptibility of glioblastoma tumors to killing by CAR T-cell immunotherapy. ...
Jun 10, 2022
0
52
A new approach from Penn Medicine researchers could cut the time it takes to alter patients' immune cells for infusion back into the body to find and attack cancer. The cell manufacturing process for this type of immunotherapy ...
Mar 29, 2022
0
133
New research from the University of Pittsburgh explains why metastatic uveal melanoma is resistant to conventional immunotherapies and how adoptive therapy, which involves growing a patient's T cells outside the body before ...
Apr 16, 2024
0
55
A new study by researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) suggests a way to re-energize critical killer ...
Jan 24, 2023
0
54
Scientists are on the hunt for a unique set of mutations, called "neoantigens," that let the immune system distinguish tumor cells from normal cells. Their goal is to help the immune system react to neoantigens and target ...
Sep 4, 2023
0
162
Researchers at the Francis Crick Institute and King's College London have identified how specialist immune cells, called gamma delta T cells (γδ T cells), sense the body's status quo, enabling them to assess the health ...
Feb 15, 2022
0
142
Researchers at the University of Zurich and Munich's LMU Klinikum hospital have studied the immune system of pairs of monozygotic twins to identify the influence of the environment and of genetics in cases of multiple sclerosis. ...
Feb 16, 2022
0
75
The treatment of blood cancers has dramatically improved in the last five years, thanks to a new class of cancer immunotherapies called CAR-T cell therapy. This therapy—which involves engineering a patient's own T cells ...
Sep 13, 2022
0
47
Immune cells called group 3 innate lymphoid cells (ILC3s) play an essential role in establishing tolerance to symbiotic microbes that dwell in the human gastrointestinal tract, according to a study led by researchers at Weill ...
Sep 7, 2022
0
105
