UK scientists slam Tamiflu drug in ongoing debate
British scientists say there isn't enough evidence to prove the antiviral drug Tamiflu reduces the spread of flu.
Apr 10, 2014
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British scientists say there isn't enough evidence to prove the antiviral drug Tamiflu reduces the spread of flu.
Apr 10, 2014
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Around half the antiviral drug Tamiflu that was prescribed during the 2009 H1N1 swine flu pandemic was never used, researchers have discovered.
Apr 17, 2013
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For the nearly 62 million Americans infected with influenza each year, oeseltamivir, commonly called Tamiflu, promises to offer relief. New research from the University of Georgia finds the medication may not have all of ...
Oct 26, 2012
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The Biden administration said Wednesday it will release doses of prescription flu medicine from the Strategic National Stockpile to states as flu-sickened patients continue to flock to hospitals and doctors' offices around ...
Dec 21, 2022
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A new study published by researchers from the University of Illinois at Chicago suggests that the drug oseltamivir—commonly known as Tamiflu—does not cause an increased risk of suicide in pediatric patients.
Mar 13, 2018
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In 2009 the influenza pH1N1 virus caused the first flu pandemic in the 21st century. The virus reached Finland in May 2009 and killed more than 50 people in the country. Since 2011 the pH1N1 virus infects Finns mainly during ...
Apr 24, 2014
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Tamiflu (the antiviral drug oseltamivir) shortens symptoms of influenza by half a day, but there is no good evidence to support claims that it reduces admissions to hospital or complications of influenza. This is according ...
Apr 11, 2014
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It doesn't take long for the flu virus to outsmart Tamiflu. EPFL scientists have developed a tool that reveals the mutations that make the virus resistant, and they have identified new mutations that may render ineffective ...
Mar 31, 2014
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Adults hospitalised with H1N1 influenza during the 2009-2010 pandemic were 25% less likely to die from the disease if they were given antiviral drugs called neuraminidase inhibitors (NAIs) such as Tamiflu, according to a ...
Mar 18, 2014
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(HealthDay)—Manufacturing problems have created a shortage of the liquid form of Tamiflu, which is designed for young children who can't swallow capsules, U.S. health officials announced Wednesday.
Jan 8, 2014
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Oseltamivir (INN) (pronounced /ɒsəlˈtæmɨvɪr/) is a drug that blocks the influenza virus from spreading between cells in the body. Thus it is an antiviral drug that is used in the treatment and prophylaxis of both Influenzavirus A and Influenzavirus B infection. Like zanamivir, oseltamivir is a neuraminidase inhibitor. It acts as a transition-state analogue inhibitor of influenza neuraminidase, preventing progeny virions from detaching from infected cells.
Oseltamivir was the first orally active neuraminidase inhibitor commercially developed. It is a prodrug, which is hydrolysed hepatically to the active metabolite, the free carboxylate of oseltamivir (GS4071). It was developed by US-based Gilead Sciences and is currently marketed by Hoffmann–La Roche (Roche) under the trade name Tamiflu. In Japan, it is marketed by Chugai Pharmaceutical Co., which is more than 50% owned by Roche. Oseltamivir is generally available by prescription only.
Roche estimates that 50 million people have been treated with oseltamivir. The majority of these have been in Japan, where an estimated 35 million have been treated. Since June 2009, Roche has been forced to allow other companies to develop competing drugs to Tamiflu, after much speculation about Roche's so-called 'monopoly' of Tamiflu in the UK.[citation needed]
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