It's a good news, bad news story. Patients whose brain tumors have a mutated enzyme called IDH1 typically live longer than those without the mutation. But even as these tumors are initially less aggressive, they always come ...
Jan 24, 2023
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A new library documenting hundreds of mutations can help to explain why some cancers don't respond to immunotherapies, and highlights potential pathways that could be drug targets in the future.
Jan 20, 2023
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Removing a single protein from cells that surround tumors can improve the sensitivity of certain cancers to immunotherapy, researchers have found.
Jan 9, 2023
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Neurodegenerative diseases affect millions of people worldwide and as our life expectancy increases, more individuals are expected to be affected in the coming decades. Tauopathies such as Alzheimer's disease are a class ...
Jan 6, 2023
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Researchers at The University of Texas MD Anderson Cancer Center have discovered a novel immunotherapy combination, targeting checkpoints in both T cells and myeloid suppressor cells, that successfully reprogrammed the tumor ...
Dec 30, 2022
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A recent study discovered a novel therapeutic target named ADAM10 that could be used to treat patients with Diabetic Retinopathy (DR), a condition that leads to blindness induced by prolonged diabetes. Abnormal blood vessel ...
Dec 22, 2022
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Less known to the general public, mucosal vaccination via the mucus membranes could provide robust protection against SARS-CoV-2 infections. Immune cells in the nose and lungs are considered better prepared to encounter and ...
Dec 16, 2022
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Pancreatic cancer remains one of the deadliest malignancies worldwide. Since five-year survival rate for pancreatic ductal adenocarcinoma (PDAC) is only about 3% in patients, PDAC is very difficult to treat with surgery worldwide. ...
Dec 15, 2022
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All living organisms on Earth are exposed to a 24-hour day-night cycle. This cycle is the reason why people rest during the darkness of night and are active during the light of day. Consequently, all human body functions ...
Dec 13, 2022
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A first-of-its-kind drug known as modakafusp alfa has shown early potential in combating multiple myeloma, a form of bone marrow cancer, in a study presented by researchers from the University of Pennsylvania's Abramson Cancer ...
Dec 12, 2022
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