A new study led by scientists at Sanford Burnham Prebys has shown that the protein RNF5 plays an unusual role in acute myeloid leukemia (AML). Unlike its expected role, marking aberrant proteins for destruction, RNF5 binds ...
Sep 13, 2021
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A new study from Linköping University has shown that the tumor-inhibiting gene TET2 is silenced in a large fraction of cases of acute lymphoblastic leukemia (ALL) in children. The scientists show that the gene can be reactivated ...
Aug 25, 2021
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Scientists have completed the largest and most diverse genetic study of Type 1 diabetes ever undertaken, identifying new drug targets to treat a condition that affects 1.3 million American adults.
Jul 22, 2021
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The new drug sotorasib reduces tumor size and shows promise in improving survival among patients with lung tumors caused by a specific DNA mutation, according to results of a global phase 2 clinical trial. The drug is designed ...
Jun 4, 2021
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A new, rapid screening approach uses CRISPR/Cas9 technology to identify immune system-related genes that play a crucial role in repairing zebrafish spinal cord injuries. Marcus Keatinge and Themistoklis Tsarouchas of the ...
Apr 29, 2021
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Genome-wide association studies (GWAS) have identified thousands of genetic variants that are associated with a wide range of diseases. But these studies often fall short of establishing what a genetic variant does to bring ...
Apr 8, 2021
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A research team led by the Icahn School of Medicine at Mount Sinai (Icahn Mount Sinai) has built the first cellular model to depict the evolution of acute myeloid leukemia (AML), from its early to late stages. By using gene ...
Feb 10, 2021
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A Swedish study has identified 17 new genes that could be targeted for treatment of psoriasis and eczema, two common hereditary skin diseases with no cure.
Oct 27, 2020
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Researchers at the Institut de Recerca Sant Joan de Déu (IRSJD) in collaboration with those at Center for Genomic Regulation (CRG) have discovered that RING1B is a critical gene for the development of Ewing sarcoma, a rare ...
Oct 23, 2020
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A new publication by scientists from Children's Medical Research Institute has challenged one of the foundations of the gene therapy field and will help to improve strategies for treating serious genetic disorders of the ...
Sep 9, 2020
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