Oncology & Cancer
Phosphoprotein biomarkers to guide cancer therapy are identified
Precision medicine in cancer treatment uses genetic changes in the cancer cells to select the best therapies for individual patients.
Jul 28, 2020
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Page 10 - News tagged with target protein
Genetics
How the regulator is regulated: Insight into immune-related protein holds therapeutic value
In immune-related disorders, therapy often involves identifying the molecules responsible for immune dysregulation and targeting them using drugs. This type of immune therapy is also used for cancer treatment, owing to the ...
Jul 21, 2020
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Oncology & Cancer
Engineered immune cells recognize, attack human and mouse solid-tumor cancer cells
A method known as CAR-T therapy has been used successfully in patients with blood cancers such as lymphoma and leukemia. It modifies a patient's own T-cells by adding a piece of an antibody that recognizes unique features ...
Jun 29, 2020
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Diseases, Conditions, Syndromes
New antivirals for influenza and Zika
Amyloids are particular protein assemblies with properties similar to silk, that serve numerous functions. They also form upon protein misfolding resulting in protein inactivation.
Jun 9, 2020
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Medical research
Researchers discover new member of novel drug family for 'undruggable' targets
In the last several years, excitement has surged for a promising class of drugs that work not by inhibiting the action of a molecular target, as most conventional drugs do, but instead by harnessing the cell's recycling system ...
Jun 4, 2020
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Medical research
Platform precisely quantifies antigens presented on cell surfaces
Normally, the immune system is able to differentiate between healthy and abnormal cells. Peptides, fragments created by the synthesis and breakdown of proteins inside each cell, are presented on the surface as antigens and ...
Jun 2, 2020
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Medical research
A new way to control Epstein-Barr virus
A team of researchers at University of Utah Health have shown the Epstein-Barr virus—which causes mononucleosis and is linked to development of several cancers—uses a novel strategy to survive. The virus takes the reins ...
May 29, 2020
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Medications
Scientists shed light on action of key tuberculosis drug
A new study led by scientists at the University of Birmingham has shed fresh light on how a key front-line drug kills the tuberculosis bacterium.
Apr 23, 2020
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Medical research
Scientists enhance new way to overcome resistance to targeted cancer treatments
Researchers have enhanced a new method for inhibiting the protein HSP72, known to be important in helping cancer cells survive and resist treatment, which will help scientists move closer to discovering a new cancer drug ...
Apr 6, 2020
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Vaccination
Racing to deliver a vaccine to the masses
Penn, together with The Wistar Institute, have conducted research that is part of the backstory of a variety of successful vaccines. Since the 1950s, their scientists have had a hand in research that undergirds widely used ...
Apr 3, 2020
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