Alzheimer's disease & dementia

Uncovering one of the driving forces of Alzheimer's disease

Alzheimer's disease, the most common form of dementia, currently has no cure or effective therapy, in part due to gaps in our understanding of how the progressive neurodegenerative disorder arises in the brain.

Medications

Technology assesses effectiveness and safety of drug targets

Researchers have boosted pioneering technology to show whether potential treatments are worth progressing into human trials, in a game-changing move that could dramatically reduce the high failure rates in drug discovery ...

Medical research

Targeting gene therapy directly into the lungs

Tufts researchers are building a reputation for precision targeting in drug delivery. Their tools: tiny lipid-based nanoparticles (LNPs) fine-tuned to latch on to specific tissues, organs, even cell types within the body. ...

Medical research

A tool to interrogate a new class of drugs

In 2014, the European Medicines Agency approved the drug Tecfidera for the treatment of relapsing multiple sclerosis, a neurodegenerative disease that affects millions of people worldwide. In multiple sclerosis, inflammation ...

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