In the last several years, excitement has surged for a promising class of drugs that work not by inhibiting the action of a molecular target, as most conventional drugs do, but instead by harnessing the cell's recycling system ...
Jun 4, 2020
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109
Researchers at Tulane University School of Medicine identified a gene that causes an aggressive form of breast cancer to rapidly grow. More importantly, they have also discovered a way to "turn it off" and inhibit cancer ...
Jun 2, 2020
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7663
Normally, the immune system is able to differentiate between healthy and abnormal cells. Peptides, fragments created by the synthesis and breakdown of proteins inside each cell, are presented on the surface as antigens and ...
Jun 2, 2020
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79
Using targeted protein degradation technology, researchers at CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences, set out to understand the primary role of a key regulator of transcription, ...
Jun 2, 2020
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58
A team of researchers at University of Utah Health have shown the Epstein-Barr virus—which causes mononucleosis and is linked to development of several cancers—uses a novel strategy to survive. The virus takes the reins ...
May 29, 2020
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432
Repurposing existing medicines focused on known drug targets is likely to offer a more rapid hope of tackling COVID-19 than developing and manufacturing a vaccine, argue an international team of scientists in the British ...
May 7, 2020
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457
An analysis of 13,000 tumors highlights two previously overlooked genes as potential new therapeutic targets for cancer treatment. The researchers have also identified potential new therapeutic targets for male infertility. ...
May 7, 2020
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6
Over the last six years a group of Estonian geneticists led by Associate Professor Agne Velthut-Meikas and Ph.D. student Ilmatar Rooda from the TalTech Department of Chemistry and Biotechnology have studied genes previously ...
May 6, 2020
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25
Korean researchers have screened 48 FDA-approved drugs against SARS-CoV-2, and found that two, that are already FDA-approved for other illnesses, seem promising. The FDA approval for other uses would greatly reduce the time ...
May 5, 2020
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18
A randomized, multicenter study of a combination of immunotherapy with a targeted therapy improved cancer control for some patients with a rare and lethal type of gastrointestinal cancer known as biliary tract cancers (BTCs). ...
May 4, 2020
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42
