Alzheimer's disease (AD) is marked by severe neurodegeneration and cognitive decline, presenting significant challenges for its prevention and treatment. Traditional hypotheses have focused on amyloid-beta plaques and Tau ...
Jul 25, 2024
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Parkinson's disease, the second most common type of progressive dementia after Alzheimer's disease, affects nearly 1 million people in the U.S. and an estimated 10 million individuals worldwide. Each year, close to 90,000 ...
Feb 23, 2024
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Alzheimer's disease has plagued one large Colombian family for generations, striking down half of its members in the prime of life. But one member of that family evaded what had seemed would be fate: Despite inheriting the ...
Dec 11, 2023
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Why do some people develop Alzheimer's disease while others don't? And, even more puzzlingly, why do many individuals whose brains are chock-full of toxic amyloid aggregates—a telltale sign of Alzheimer's brain pathology—never ...
May 29, 2023
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Evidence in mouse and human brain tissue reveals a mechanism that may explain the sex-based differences in Alzheimer's disease, including why females are more vulnerable. Researchers report October 4 in the journal Cell that ...
Oct 4, 2022
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Newly discovered cellular hot spots of a potentially toxic protein could open new research avenues into how Alzheimer's disease progresses in the brain.
Sep 13, 2022
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Aliria Rosa Piedrahita de Villegas should have developed Alzheimer's disease in her 40s and died from the disease in her 60s because of a rare genetic mutation.
Jul 28, 2022
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Research led by neuroscientists at The Ohio State University College of Medicine provides insights into mechanisms that underpin selective neuronal vulnerability, which could help in developing new therapeutics to prevent ...
Apr 11, 2022
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An experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to save brain function.
Jun 14, 2021
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In three recent publications in Molecular Psychiatry, Brain and JAMA Neurology researchers from the University of Gothenburg provide convincing evidence that an in-house developed blood test for Alzheimer's disease can detect ...
Jan 13, 2021
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