In the years since her lab discovered that exposing Alzheimer's disease model mice to light flickering at the frequency of a key brain rhythm could stem the disorder's pathology, MIT neuroscientist Li-Huei Tsai and her team ...
Oct 22, 2019
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A collaborative study published today in the journal Cell Reports provides evidence for a new molecular cause for neurodegeneration in Alzheimer's disease. The study, led by researchers at Baylor College of Medicine and the ...
Oct 8, 2019
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Scientists have visualised for the first time protein 'tangles' associated with dementia in the brains of patients who have suffered a single head injury.
Sep 4, 2019
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Like a sorting machine in an assembly line, a molecule known as VPS35 detects and removes defective proteins from neurons. And similar to other quality control processes, the VPS35 system goes a long way toward protecting ...
Jul 9, 2019
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A study by investigators at Massachusetts General Hospital (MGH) finds evidence that spread through the brain of the Alzheimer's-disease-associated protein tau is facilitated by factors within the aging brain itself and not ...
Jun 26, 2019
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Two proteins central to the pathology of Alzheimer's disease act as prions—misshapen proteins that spread through tissue like an infection by forcing normal proteins to adopt the same misfolded shape—according to new ...
May 1, 2019
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A study from Massachusetts General Hospital (MGH) investigators sheds new light on how the hallmarks of Alzheimer's disease—amyloid-beta (A-beta) plaques and neurofibrillary tangles containing the protein tau—produce ...
Dec 19, 2018
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Some neurons in the brain protect themselves from Alzheimer's with a cellular cleaning system that sweeps away toxic proteins associated with the disease, according to a new study from Columbia University and the University ...
Dec 17, 2018
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Zombie cells are the ones that can't die but are equally unable to perform the functions of a normal cell. These zombie, or senescent, cells are implicated in a number of age-related diseases. And with a new letter in Nature, ...
Sep 19, 2018
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Scientists have discovered a "Big Bang" of Alzheimer's disease – the precise point at which a healthy protein becomes toxic but has not yet formed deadly tangles in the brain.
Jul 10, 2018
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