New imaging of patients with Alzheimer's demonstrates how a telltale protein spreads throughout the brain based on the phenotype of the disease, i.e., whether the condition is dominated by forgetfulness, or atrophy in a specific ...
A mechanism has been found that controls cellular levels of tau, a protein whose abnormal accumulation is at the root of tauopathies, a class of devastating neurodegenerative diseases.
Oct 21, 2022
1
55
Alzheimer's disease (AD) currently has no cure and is predicted to affect over 100 million people worldwide by 2050. Ongoing research is focused on two key neurotoxic proteins: amyloid beta (Aβ) and tau. While these proteins ...
Oct 17, 2022
0
16
Early cognitive decline may result from a shift in the ratio of a protein sub-type in our brain cells triggering cell-loss. This new study, published in Scientific Reports, shows how this might be caused. The discovery provides ...
Oct 10, 2022
0
49
Evidence in mouse and human brain tissue reveals a mechanism that may explain the sex-based differences in Alzheimer's disease, including why females are more vulnerable. Researchers report October 4 in the journal Cell that ...
Oct 4, 2022
0
42
Neurons in an area of the brain responsible for memory (known as the entorhinal cortex) were significantly larger in super agers (80 years and older) compared to cognitively average peers, individuals with early-stage Alzheimer's ...
Sep 30, 2022
0
156
Researchers at the School of Dentistry, University of Central Lancashire (UCLan) were the first to report the link between gum disease and Alzheimer's disease.
Sep 22, 2022
0
1496
Scientists at UCLA have used a molecule found in green tea to identify additional molecules that could break up protein tangles in the brain thought to cause Alzheimer's and similar diseases.
Sep 20, 2022
0
100
Newly discovered cellular hot spots of a potentially toxic protein could open new research avenues into how Alzheimer's disease progresses in the brain.
Sep 13, 2022
0
6
Using a novel 3D imaging technology, researchers at Karolinska Institutet, among others, have been able to comprehensively characterize a part of the brain that shows perhaps the earliest accumulation of tau protein, an important ...
Aug 31, 2022
0
94
