Alzheimer's disease & dementia

New drug targets early instigator of Alzheimer's disease

Over a hundred years after they were first identified, two ominous signposts of Alzheimer's disease (AD) remain central topics of research—both formed by sticky accumulations of protein in the brain. Amyloid beta solidifies ...

Alzheimer's disease & dementia

Alzheimer's disease destroys neurons that keep us awake

Researchers and caregivers have noted that excessive daytime napping can develop long before the memory problems associated with Alzheimer's disease begin to unfold. Prior studies have considered this excessive daytime napping ...

Alzheimer's disease & dementia

Blood tests for Alzheimer's: Why new studies are encouraging

Many people who have problems with their memory, especially if they are elderly, worry that they have Alzheimer's disease, which afflicts at least 5.5 million people in the U.S. and brings tremendous burdens to families as ...

Alzheimer's disease & dementia

Risk and progression of Alzheimer's disease differ by sex

The abnormal accumulation of proteins in the brain is a biological marker for Alzheimer's disease, but the ways in which these proteins spread may help explain why the prevalence of Alzheimer's is higher in women than in ...

Medical research

Alzheimer's disease protein links plaques to cell death in mice

A new protein involved in Alzheimer's disease (AD) has been identified by researchers at the RIKEN Center for Brain Science (CBS). CAPON may facilitate the connection between the two most well-known AD culprits, amyloid plaques ...

Alzheimer's disease & dementia

Alzheimer's disease is a 'double-prion disorder,' study shows

Two proteins central to the pathology of Alzheimer's disease act as prions—misshapen proteins that spread through tissue like an infection by forcing normal proteins to adopt the same misfolded shape—according to new ...

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