A new study by investigators from Mass General Brigham has found that a brief, simulated task of navigating a phone menu can detect the earliest changes in daily functioning in people at risk of developing Alzheimer's disease. ...
Jun 14, 2023
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Dementia is defined as the loss of cognitive functioning—including thinking, remembering, and reasoning—and is very prevalent in Japan. Currently, the treatment satisfaction for dementia is among the lowest and no drug ...
May 29, 2023
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Fresh insights into the spread of damaging proteins that build up in the brains of people with Alzheimer's disease could hold the key to stopping the condition from progressing, a study says.
May 15, 2023
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Inhibition of the PREP enzyme was successful in stopping the progression of frontotemporal dementia in a mouse model of the disease, according to a new study published in Science Translational Medicine. PREP inhibitor treatment ...
Apr 13, 2023
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To date, the search for effective treatments for dementia has yielded only disappointments. Many recent drug candidates target the tau protein, which aggregates and forms tangles in patients' brain tissue and is involved ...
Apr 7, 2023
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People who eat diets rich in green leafy vegetables as well as other vegetables, fruits, whole grains, olive oil, beans, nuts and fish may have fewer amyloid plaques and tau tangles in their brain—signs of Alzheimer's disease—than ...
Mar 8, 2023
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Several progressive neurodegenerative disorders, including Alzheimer's disease, are defined by having tau proteins in the brain. Researchers are seeking to identify the mechanisms behind these tau proteins to develop treatments, ...
Jan 31, 2023
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Alzheimer's disease (AD) currently has no cure and is predicted to affect over 100 million people worldwide by 2050. Ongoing research is focused on two key neurotoxic proteins: amyloid beta (Aβ) and tau. While these proteins ...
Oct 17, 2022
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Newly discovered cellular hot spots of a potentially toxic protein could open new research avenues into how Alzheimer's disease progresses in the brain.
Sep 13, 2022
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New research has revealed how the tau protein, a critical element in the formation of Alzheimer's disease, is also involved in normal learning processes in the healthy brain—potentially providing a focal point for future ...
Aug 23, 2022
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