Alzheimer's disease is the most common and best known of the tauopathies, a set of neurodegenerative brain diseases caused by toxic tangles of the protein tau. A study by researchers at Washington University School of Medicine ...
Mar 18, 2022
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In her latest research paper, published in the Journal of Molecular Neuroscience, Anne Robinson, Head of Carnegie Mellon's Department of Chemical Engineering, explains why understanding the progression of neurodegeneration ...
Jan 21, 2022
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Utilizing cutting-edge proteomics, researchers at the Buck Institute and elsewhere have mapped the "tau interactome" uncovering new findings about the role of tau in neurodegenerative disease. Publishing in Cell, scientists ...
Jan 20, 2022
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An international team led by Case Western Reserve University's School of Medicine has made a significant breakthrough in understanding why Alzheimer's disease progresses so rapidly in some people that they die within three ...
Jan 5, 2022
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Just as a home security system can alert a homeowner to the presence of an intruder, a protein called polyglutamine binding protein-1 (PQBP1) found in brain cells can alert the body to the presence of "intruding" viruses ...
Dec 8, 2021
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A new Cleveland Clinic-led study has identified sildenafil—an FDA-approved therapy for erectile dysfunction (Viagra) and pulmonary hypertension (Ravatio)—as a promising drug candidate to help prevent and treat Alzheimer's ...
Dec 6, 2021
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Prevailing theories posit plaques in the brain cause Alzheimer's disease. New UC Riverside research instead points to cells' slowing ability to clean themselves as the likely cause of unhealthy brain buildup.
Nov 29, 2021
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Existing and emerging cancer drugs could be repurposed as therapies to be tested in clinical trials for people at genetic risk of Alzheimer's disease, according to a new study published in Science Advances. Research combining ...
Nov 10, 2021
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With the school year well on its way, we all recognize the importance of getting students energized. However, we also know that overstimulated children can wreak havoc on a classroom, leaving a teacher trying to regain control ...
Oct 19, 2021
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Abnormal accumulation of misfolded tau protein in filaments characterizes numerous neurodegenerative diseases—collectively called tauopathies for this very reason. A long-standing collaboration between Michel Goedert's ...
Sep 30, 2021
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