Diseases, Conditions, Syndromes

How drug resistant TB evolved and spread globally

The most common form of Mycobacterium tuberculosis (TB) originated in Europe and spread to Asia, Africa and the Americas with European explorers and colonialists, reveals a new study led by UCL and the Norwegian Institute ...

Diseases, Conditions, Syndromes

Inching closer to a soft spot in isoniazid-resistant tuberculosis

Antibiotic-resistant tuberculosis is a public health threat. TB and other bacteria become resistant to antibiotics by evolving genetic changes over time, which they can do quite quickly because bacterial lifecycles are short. ...

Diseases, Conditions, Syndromes

New TB drugs at risk of developing resistance: experts

New drugs for hard-to-treat tuberculosis strains may be fast rendered ineffective themselves if incorrectly used, a report warned Thursday, on the eve of World TB Day.

Diseases, Conditions, Syndromes

Surprising diversity of TB strains found in Ethiopia

Ethiopia is a hotspot for tuberculosis (TB) infection, ranking third among African countries and eighth in the world for TB burden according to the World Health Organization. But, say researchers who have analyzed the genomes ...

Diseases, Conditions, Syndromes

Researchers report breakthrough in tuberculosis research

Scientists from the PATHONGEN-TRACE project in Germany and France together with colleagues from the Oxford Biomedical Research Centre and the South African National Institute for Communicable Diseases developed a new genetic ...

Diseases, Conditions, Syndromes

New drug regimen speeds TB treatment

An experimental cocktail of three drugs can dramatically shorten the time it takes to treat patients infected with TB strains that are hard to cure with conventional antibiotics, according to research presented Monday at ...

Diseases, Conditions, Syndromes

Host genetics can contribute to lung damage in severe tuberculosis

A third of the global population is infected with the bacterial pathogen, a mycobacterium, that causes tuberculosis (TB). Most carriers control the infection and are asymptomatic, but severe forms of the disease (more common ...

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