Autosomal dominant polycystic kidney disease (ADPKD) is the most common potentially lethal genetic disease—about a half million people in the United States alone suffer from the condition. There is no cure, but new research ...
Apr 3, 2023
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In a recently published editorial in the journal Genes & Cancer, researcher Tatsuro Jo from the Japanese Red Cross Nagasaki Genbaku Hospital's Department of Hematology discussed aggressive type adult T-cell leukemia/lymphoma ...
Feb 27, 2023
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A gene therapeutic approach that shows promise for treating age-related macular degeneration (AMD) may also be effective in treating other eye conditions such as glaucoma. It provided benefit in three additional models of ...
Jan 30, 2023
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Many cardiovascular diseases, such as atherosclerosis, or "hardening of the arteries," correlate to mitochondrial dysfunction and endothelial impairment in the tissues of the heart and blood vessels. Despite a significant ...
Jan 24, 2023
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The Hidetoshi Sakurai Laboratory at CiRA has successfully reproduced the pathology of Myotonic Dystrophy type 1 (DM1) using skeletal muscle cells generated from patient-derived iPS cells and demonstrated their use for quantitative ...
Jan 12, 2023
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A research group led by CiRA Junior Associate Professor Kazuo Takayama and Associate Professor Yoshiaki Okada of Osaka University has revealed that SARS-CoV-2 disrupts the vascular endothelial barrier by suppressing the expression ...
Sep 28, 2022
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Swiss pharmaceuticals company Novartis said Thursday that it plans to spin off its generics subsidiary Sandoz, which generated nearly $10 billion in revenue last year.
Aug 25, 2022
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As SARS-CoV-2 has evolved and mutated, therapeutic antibodies that worked early in the pandemic have become less effective, and newer variants, especially omicron, have developed ways to evade the antibodies we make in response ...
Aug 11, 2022
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The tumor biomarker research team from the Suzhou Institute of Biomedical Engineering and Technology of the Chinese Academy of Sciences recently reported that DMDRMR/miR-378a-5p/ DAB2IP axis promotes angiogenesis and sunitinib ...
May 25, 2022
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Delivered using adenovirus (Ad) vectors, therapeutic genes address the cause of disease—not just the symptoms. However, while advances in the understanding of human diseases and the genome have led to an increasing number ...
May 11, 2022
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