A gene therapeutic approach that shows promise for treating age-related macular degeneration (AMD) may also be effective in treating other eye conditions such as glaucoma. It provided benefit in three additional models of ...
Jan 30, 2023
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A new clinical and preclinical study from UCLA Jonsson Comprehensive Cancer Center identifies the DNA roots of resistance to targeted cancer therapy, providing a possible strategy to address a vexing issue in cancer therapeutics. ...
Jan 26, 2023
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It's a good news, bad news story. Patients whose brain tumors have a mutated enzyme called IDH1 typically live longer than those without the mutation. But even as these tumors are initially less aggressive, they always come ...
Jan 24, 2023
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Many cardiovascular diseases, such as atherosclerosis, or "hardening of the arteries," correlate to mitochondrial dysfunction and endothelial impairment in the tissues of the heart and blood vessels. Despite a significant ...
Jan 24, 2023
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Interleukin (IL)-15 is a cytokine with different modes of action, and a new article describes why it is important to selectively target the mode of action of the cytokine rather than IL-15 itself to inhibit its activity. ...
Jan 23, 2023
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Nearly one quarter of hospitalized people experience a harmful event during their stay, a new study finds.
Jan 14, 2023
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For patients suffering from sudden illnesses such as myocardial infarction and severe hypoglycemia, prompt administration of emergency medications is imperative, otherwise they may be at great risk of death. Actually, a large ...
Jan 12, 2023
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The Hidetoshi Sakurai Laboratory at CiRA has successfully reproduced the pathology of Myotonic Dystrophy type 1 (DM1) using skeletal muscle cells generated from patient-derived iPS cells and demonstrated their use for quantitative ...
Jan 12, 2023
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It was 1985 and John Lawn had seen enough.
Jan 9, 2023
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Patient-reported outcomes from individuals diagnosed with relapsed or refractory large B-cell lymphoma revealed that those who received axicabtagene ciloleucel (axi-cel) immunotherapy experienced higher quality of life than ...
Jan 4, 2023
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