Medical research

Preclinical study offers hope for Hirschsprung's disease

Babies with Hirschsprung's disease are born with an incomplete or absent gut nervous system. Children's Hospital Los Angeles investigator Tracy Grikscheit, MD, runs a laboratory that investigates the therapeutic potential ...

Diseases, Conditions, Syndromes

Liver fibrosis 'off switch' discovered in mice

Chronic alcohol abuse and hepatitis can injure the liver, often leading to a buildup of collagen and scar tissue. Understanding this process, known as liver fibrosis, could help researchers develop new ways to prevent or ...

Medical research

New cellular player involved in obesity discover

The prevalence of obesity, a disease considered a serious public health problem, is increasing globally. In Portugal, almost half of the population is overweight and close to one million adults suffer from obesity. Known ...

Oncology & Cancer

Study shows how circulating tumor cells target distant organs

Most cancers kill because tumor cells spread beyond the primary site to invade other organs. Now, a USC study of brain-invading breast cancer cells circulating in the blood reveals they have a molecular signature indicating ...

Oncology & Cancer

How lymphoma cells metastasize to the brain

Lymphomas in the central nervous system are rare but dangerous. Scientists at the German Cancer Research Center (DKFZ) have now discovered which molecular mechanism leads to lymphomas forming metastases in the central nervous ...

Medical research

Heart-on-a-chip mimics drug response seen in humans

Researchers from TARA Biosystems, Inc. and GlaxoSmithKline (GSK) today published data demonstrating that TARA's engineered heart-on-a-chip system replicated drug responses found in adult humans. The findings, published in ...

Diseases, Conditions, Syndromes

Shaky scaffold changes lung infrastructure

Our lungs work tirelessly all through the day to keep us breathing, seamlessly expanding and contracting. When lung tissue becomes damaged and scarred, it can lose its flexibility, making it harder to breathe.

Medical research

A critical factor for wound healing

The p53 family of transcription factors (p63 and p73) plays critical roles in keratinocyte (skin cell) function.

page 18 from 33