Diseases, Conditions, Syndromes

3D organoid models show brain mechanisms of Tourette syndrome

Tourette syndrome (TS) is a common disorder characterized by uncontrollable motor or vocal tics that manifests in childhood and can interfere with school performance, relationships, and quality of life. Using stem cells from ...

Genetics

Another byproduct of aging: Hypermutations in the brain

Genetic mutations in early development have been implicated in several psychiatric disorders such as autism and schizophrenia, symptoms of which typically manifest during childhood and early adulthood. However, mutations ...

Medical research

Predicting the chaos in Tourette syndrome tics

During the pandemic, news reports surfaced of a surge of young adults showing up at doctors' offices with unexplainable movement disorders that looked, perhaps to a non-specialist, a little bit like Tourette syndrome.

Neuroscience

Identifying the neural network responsible for how tics develop

A team of researchers from Charité – Universitätsmedizin Berlin has identified a neural network which is responsible for generating tic disorders. Targeting of this network via deep brain stimulation delivered by a ...

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