Medical research

Scientists present an effective drug toxicity prediction method

Researchers from Skoltech (Maxim Fedorov's group, CDISE) and the German Research Center for Environmental Health, Helmholtz Zentrum München (HMGU; Igor Tetko's group) have developed an enhanced drug candidate toxicity prediction ...

Medical research

Blocking toxic-protein production in ALS

Patients with ALS frequently have a string of repeated DNA code in the cells of their brain, carrying hundreds to thousands of copies within the gene C9orf72. New research looks at what triggers these repeated sequences to ...

Neuroscience

Study yields new insight on how memory works

Two Veterans Affairs researchers have explored how memory is tied to the hippocampus, with findings that will expand scientists' understanding of how memory works.

Psychology & Psychiatry

How to discontinue antidepressants

There has been a lot of attention to problems patients face in discontinuing antidepressant drugs. However, there appear to be few indications, particularly in guidelines and reviews. In an article in the current issue of ...

Oncology & Cancer

Cellular pumps protect the gut from toxins

The master regulators of gut stem cells, called intestinal myofibroblasts, have pumps that protect them, and thus the gut, from the toxic effects of a wide range of compounds, including the anticancer drug tamoxifen, according ...

Medications

Curbs on legal highs cut need for hospital care

Fewer people sought hospital treatment for the toxic effects of so-called legal highs following temporary restrictions, a study based at an Edinburgh hospital suggests.

Medical research

Improving drug treatments with natural products

Turmeric, shrimp shells, beeswax and cocoa butter are being used to improve the effectiveness of drugs and reduce side effects when treating a range of diseases including cancer and diabetes.

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