Microbiome could be culprit when good drugs do harm
People sometimes suffer toxic side effects from drugs that help many others. Yale scientists have identified a surprising explanation—the gut microbiome.
Feb 8, 2019
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People sometimes suffer toxic side effects from drugs that help many others. Yale scientists have identified a surprising explanation—the gut microbiome.
Feb 8, 2019
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Researchers from Skoltech (Maxim Fedorov's group, CDISE) and the German Research Center for Environmental Health, Helmholtz Zentrum München (HMGU; Igor Tetko's group) have developed an enhanced drug candidate toxicity prediction ...
Jan 25, 2019
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Patients with ALS frequently have a string of repeated DNA code in the cells of their brain, carrying hundreds to thousands of copies within the gene C9orf72. New research looks at what triggers these repeated sequences to ...
Jan 22, 2019
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Two Veterans Affairs researchers have explored how memory is tied to the hippocampus, with findings that will expand scientists' understanding of how memory works.
Dec 26, 2018
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There has been a lot of attention to problems patients face in discontinuing antidepressant drugs. However, there appear to be few indications, particularly in guidelines and reviews. In an article in the current issue of ...
Dec 13, 2018
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A breakthrough has been made in the fight against Alzheimer's disease—researchers have found a new way to target the toxic particles that destroy healthy brain cells.
Sep 24, 2018
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The master regulators of gut stem cells, called intestinal myofibroblasts, have pumps that protect them, and thus the gut, from the toxic effects of a wide range of compounds, including the anticancer drug tamoxifen, according ...
Aug 24, 2018
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Fewer people sought hospital treatment for the toxic effects of so-called legal highs following temporary restrictions, a study based at an Edinburgh hospital suggests.
Jul 25, 2018
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Turmeric, shrimp shells, beeswax and cocoa butter are being used to improve the effectiveness of drugs and reduce side effects when treating a range of diseases including cancer and diabetes.
May 25, 2018
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Prion diseases are slow degenerative brain diseases that occur in people and various other mammals. No vaccines or treatments are available, and these diseases are almost always fatal. Scientists have found little evidence ...
May 17, 2018
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