Two new treatments are showing promise and overall survival is on the rise for AL amyloidosis, according to a series of studies involving researchers in the Abramson Cancer Center and the Perelman School of Medicine at the ...
Dec 1, 2016
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A new study from The University of Texas Medical Branch at Galveston offers important insight into how Alzheimer's disease begins within the brain. The researchers found a relationship between inflammation, a toxic protein ...
Nov 18, 2016
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Synapses, the place where brain cells contact one another, play a pivotal role in the transmission of toxic proteins. This allows neurodegenerative diseases such as Alzheimer's to spread through the brain. This the main conclusion ...
Nov 9, 2016
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The recent ability to peer into the brain of living individuals with a rare type of language dementia, primary progressive aphasia (PPA), provides important new insights into the beginning stages of this disease—which results ...
Mar 7, 2016
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A toxic protein called amyloid beta is thought to play a key role in the onset of Alzheimer's disease. In healthy people, amyloid beta is degraded by enzymes as it forms. However, in patients with the disease, these enzymes ...
Mar 2, 2016
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Immunotherapy to ameliorate neurodegeneration by targeting brain protein aggregates with antibodies is an area of intense investigation. A study published on January 28th in PLOS Pathogens examines seemingly contradictory ...
Jan 28, 2016
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A group of researchers has shown for the first time in cells and in a mouse model that a drug used to treat cancer can neutralize the toxic RNA that causes the prolonged muscle contractions and other symptoms of myotonic ...
Dec 10, 2015
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An FDA-approved drug for leukemia improved cognition, motor skills and non-motor function in patients with Parkinson's disease and Lewy body dementia in a small phase I clinical trial, report researchers at Georgetown University ...
Oct 18, 2015
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Researchers in the US have used rats and mice to explore how sleep posture alters the way in which toxic proteins are cleared from the brain. The research was published in the Journal of Neuroscience on 10 August.
Aug 13, 2015
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A new test developed by UBC researchers allows physicians to measure the effects of gene silencing therapy in Huntington's disease and will support the first human clinical trial of a drug that targets the genetic cause of ...
Aug 7, 2015
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