Opioid receptors are proteins in the central nervous system that are targeted by opioid drugs for pain relief. There are three subtypes of opioid receptors, MOP, DOP and KOP, in addition to the opioid-related NOP receptor.
The neurons in our nervous system "talk" to each other by sending and receiving chemical messages called neurotransmitters. This communication is facilitated by cell membrane proteins called receptors, which pick up neurotransmitters ...
Apr 1, 2021
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Decades before the first symptoms of Alzheimer's appear, the brain's neurons start secreting tau proteins, one of the first changes known to occur in the course of the disease.
Nov 25, 2020
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Glutamate is the major excitatory neurotransmitter in the brain, and the postsynaptic expression level of glutamate receptors is a critical factor in determining the efficiency of information transmission and the activity ...
Nov 19, 2018
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Northwestern Medicine scientists have discovered a new cause of Parkinson's disease—mutations in a gene called TMEM230. This appears to be the third gene definitively linked to confirmed cases of the common movement disorder.
Jun 6, 2016
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Newly published research by Indiana University structural biologist Joel Ybe and colleagues identifies a "topology switch" in the protein clathrin, the function of which may shed light on molecular processes involved in tumor ...
Jan 13, 2013
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When three teenagers died of fentanyl overdoses last year in Larimer County, Colorado, it shocked the community and "flipped families upside down," said Tom Gonzales, the county's public health director.
Sep 29, 2023
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Victims' agency and needs, independent of their desire to exit trafficking, should be the focus of health care services for individuals who have been sexually exploited, concludes a new study by researchers with McGill University's ...
Aug 30, 2023
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Tobacco companies claim to be transforming their business by "reducing the health impact" of their products. Yet they often oppose the very policies that could achieve this goal.
May 3, 2023
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Congressional leaders introduced a bill on Tuesday that would further restrict access to the veterinary drug xylazine, which is now being added to fentanyl powder.
Mar 29, 2023
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