Genetics
Genes that form specific bones in the womb heal them later in life, finds study
Genes long known to control the formation of bones before birth also control bone healing later in life, a new study found.
Mar 20, 2023
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Page 6 - News tagged with transcription factors
Oncology & Cancer
Researchers identify key source of T cell 'exhaustion'
Custom-made to attack cancer cells, CAR T-cell therapies have opened a new era in the treatment of human cancers, particularly, in hematologic malignancies. All too often, however, they display a frustrating trait inherited ...
Mar 20, 2023
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Immunology
Study shows immune cells have a backup mechanism
The enzyme TBK1 is an important component of the innate immune system that plays a critical role in the defense against viruses. Upon mutation-induced loss of TBK1 function, patients show an increased susceptibility to viral ...
Mar 10, 2023
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Genetics
Researchers analyze genetic and epigenetic regulators to understand severity discrepancies in COVID-19
Infection with SARS-CoV-2 leads to severe disease in some people, while others do not get ill or only experience mild symptoms. But why is this the case? Unfortunately, we do not know exactly. We do know that an overactive ...
Feb 23, 2023
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Genetics
The best genetic predictors of heart arrhythmia and hidden comorbidity
In the largest genetic study of heart arrhythmia to date, researchers led by Kazuo Miyazawa and Kaoru Ito at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan report the discovery of several genes and individual ...
Jan 19, 2023
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Oncology & Cancer
Scientists detail major mechanism lung cancers use to evade immune attack
A protein commonly found at high levels in lung cancer cells controls a major immunosuppressive pathway that allows lung tumors to evade immune attack, according to a study led by researchers at Weill Cornell Medicine. The ...
Jan 10, 2023
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Medical research
The molecules behind metastasis
Many cancer cells never leave their original tumors. Some cancer cells evolve the ability to migrate to other tissues, but once there cannot manage to form new tumors, and so remain dormant. The deadliest cancer cells are ...
Jan 5, 2023
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Gerontology & Geriatrics
Research illuminates approaches for long-term hearing loss treatment
About 430 million people around the world experience disabling hearing loss. In the United States, approximately 37.5 million adults report some trouble hearing. Hearing loss can happen when any part of the ear or the nerves ...
Dec 8, 2022
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Medical research
Early life experiences can have long-lasting impact on genes
Early life experiences can impact the activity of our genes much later on and even affect longevity, finds a new study in fruit flies led by UCL researchers.
Dec 1, 2022
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Medical research
Ganglion cells created in mice in bid to fix diseased eyes
While fish, reptiles and even some birds can regenerate damaged brain, eye and spinal cord cells, mammals cannot. For the first time, non-neuronal cells have been induced to mimic specific ganglion cells in the eyes of mice.
Nov 30, 2022
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