While bright light helps us see better, our eyes need darkness for better vision. Light breaks down the sensitive machinery of our eyes every day, and during the darkness of night, key pieces are rebuilt. The clock of our ...
Mar 8, 2022
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A decade ago researchers announced development of a cancer immunotherapy called CAR (for chimeric antigen receptor)-T, in which a patient is re-infused with their own genetically modified T cells equipped to mount a potent ...
May 27, 2019
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Lymphomas in the central nervous system are rare but dangerous. Scientists at the German Cancer Research Center (DKFZ) have now discovered which molecular mechanism leads to lymphomas forming metastases in the central nervous ...
Sep 16, 2019
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How does one's experience of an event get translated into a memory that can be accessed months, even years later? A team led by University of Pennsylvania scientists has come closer to answering that question, identifying ...
Sep 10, 2012
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A good vitamin D status is beneficial both in cancer prevention and in the prognosis of several cancers, according to a new research review. The anti-cancer effects of vitamin D are especially pronounced in the prevention ...
Jun 10, 2020
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The powerful master regulatory transcription factor called Bcl6 is key to the survival of a majority of aggressive lymphomas, which arise from the B-cells of the immune system. The protein has long been considered too complex ...
Mar 3, 2013
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Researchers at Children's Hospital of Philadelphia (CHOP) have pinpointed a genetic variation responsible for driving the development of inflammatory bowel disease (IBD). The genetic pathway associated with this variation ...
Apr 9, 2020
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Cells, like ordinary households, produce "garbage" – debris and dysfunctional elements – that need disposal. When the mechanism for taking out this garbage fails, rare genetic diseases called lysosomal storage disorders ...
May 26, 2011
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Researchers, using a method called genome-wide association study, have illuminated the genetic underpinnings of high serum urate, the blood condition that brings on gout. The study, co-led by scientists at the Johns Hopkins ...
Oct 7, 2019
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A major international study has identified a novel gene mutation that appears to increase the risk of both inherited and sporadic cases of malignant melanoma, the most deadly form of skin cancer. The identified mutation occurs ...
Nov 13, 2011
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