Medical research

Cryptic transcription in mammalian stem cells linked to aging

Although visible signs of aging are usually unmistakable, unraveling what triggers them has been quite a challenge. Researchers at Baylor College of Medicine and collaborating institutions have discovered that a cellular ...

Medical research

Gene expression mechanism may have immunity, cancer implications

Alternative polyadenylation (APA) is an RNA processing mechanism that regulates gene expression by generating different ends on RNA transcripts of the same gene. Though it affects more than half of human genes, the significance ...

Diseases, Conditions, Syndromes

Revealing the mystery behind non-alcoholic liver disease

Non-alcoholic fatty liver disease is the most common liver disorder worldwide and is present in approximately 25 percent of the world's population. Over 90 percent of obese, 60 percent of diabetic, and up to 20 percent of ...

Oncology & Cancer

Novel class of drugs may help treat deadly lymphoma

A new class of drugs that inhibits a 'master switch' involved in the vast majority of cases of mantle cell lymphoma (MCL), a fatal subtype of non-Hodgkin's lymphoma, has been discovered by researchers at Mount Sinai.

Cardiology

Converting scar tissue to heart muscle after a heart attack

It is estimated that during a heart attack, one billion cells in the heart are lost. In the wake of the heart attack, the lost tissue is replaced by scar tissue, which can lead to heart failure, arrhythmia and death. In a ...

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