The RAS pathway is a cellular signaling pathway that regulates growth and development in humans. RASopathies are a group of diseases characterized by defects in RAS signaling.
Feb 8, 2013
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Patients with advanced hepatocellular (or liver) cancer have high mortality rates, with existing drugs demonstrating only a small, but significant survival advantage. By combining a zebrafish model of liver cancer with data ...
Jan 30, 2014
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Mysterious brain cells called microglia are starting to reveal their secrets thanks to research conducted at the Weizmann Institute of Science.
Nov 25, 2013
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Scientists at the Nencki Institute of Experimental Biology of the Polish Academy of Sciences in Warsaw investigate mice with a very precisely modified genome. Because it is possible to turn off the Dicer gene in adult mice, ...
Apr 25, 2013
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Researchers have identified a unique type of neutrophil significantly associated with Alzheimer's disease (AD) pathology and mapped the transcriptome of neutrophils in the peripheral blood of AD mice. The study was published ...
Jul 24, 2024
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A new study shows that subretinal adeno-associated virus 8 (AAV8) injections cause proinflammatory T-cell immune response against the transgene product. According to the study, published in the journal Human Gene Therapy, ...
Jul 18, 2024
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Advanced engineering of a mini-intronic plasmid (MIP) system designed to carry a therapeutic gene can significantly enhance the expression of the transgene delivered using an adeno-associated viral (AAV) vector. The ability ...
Jan 27, 2017
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Imagine if we could inhale scents that delay the onset of cancer, inflammation, or neurodegenerative disease. Researchers at the University of California, Riverside, are poised to bring this futuristic technology closer to ...
Feb 27, 2024
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Panama will try to control a dengue outbreak that has claimed six lives this year by releasing transgenic mosquitoes to render infertile female transmitters of the disease, officials said.
Jan 15, 2014
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Scientists have found a way to simultaneously monitor the switching on and off of circadian "clock" genes and their effects on mouse behaviour in real-time.
Jun 20, 2016
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