Vaccination
Canada secures deals for millions of COVID-19 vaccine doses
Canada announced deals on Monday with US companies Novavax and Johnson & Johnson for millions doses of their experimental COVID-19 vaccines.
Aug 31, 2020
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Page 3 - News tagged with trial phase
Medical research
Study shows new medication effectively treats underlying cause of cystic fibrosis
A new study has confirmed that the drug, ivacaftor (VX-770), significantly improves lung function in some people with cystic fibrosis (CF). The results of the phase III clinical trial study, "A CFTR Potentiator in Patients ...
Nov 2, 2011
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Arthritis & Rheumatism
Newly approved oral medication slows rheumatoid arthritis joint damage
A Phase 3 clinical trial demonstrates that tofacitinib improves disease activity and inhibits progression of joint damage in rheumatoid arthritis (RA) patients who did not respond to methotrexate (MTX). Results of the 12-month ...
Jan 24, 2013
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Oncology & Cancer
With early, obvious benefit of a targeted cancer drug, should expensive clinical testing continue?
Generally, FDA-approved clinical trials progress through three phases: the first shows safety, the second starts to explore effects and the third seeks to prove a drug's superiority over existing treatments. But when a drug's ...
Aug 8, 2013
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Cardiology
Prasugrel versus clopidogrel for ACS patients managed without revascularisation
The first trial to study the effect of platelet inhibition in patients with acute coronary syndromes managed medically without revascularisation has found no significant difference between prasugrel and clopidogrel in the ...
Aug 27, 2012
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Oncology & Cancer
For advanced prostate cancer, new drug slows disease
A new medication proved effective in slowing the spread of metastatic prostate cancer, while helping to maintain the quality of life, in patients with advanced disease. The phase 3 study was unblinded midway, allowing patients ...
Jun 2, 2012
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Medications
Largest study to date of lebrikizumab supports its use for treatment of atopic dermatitis
Two phase 3 trials suggest that a 16 week treatment with a drug called lebrikizumab was effective in adults and adolescents with moderate to severe dermatitis, according to a paper published in the New England Journal of ...
Mar 15, 2023
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Oncology & Cancer
Treatment for lupus enters phase III
Lupuzor may become the first specific and non-immunosuppressant therapy for lupus, a disabling autoimmune disease that is currently incurable. Discovered by Sylviane Muller's team in the CNRS Immunopathologie et Chimie Thérapeutique ...
Dec 15, 2015
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Oncology & Cancer
Dual HER2 blockade significantly extends progression-free survival
Adding pertuzumab to a combination of trastuzumab and docetaxel chemotherapy extended progression-free survival by a median of 6.1 months in patients with metastatic HER2-positive breast cancer compared with patients who ...
Dec 8, 2011
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Diseases, Conditions, Syndromes
Team assessing if dual-antibody injection prevents COVID-19 illness
A combination antibody treatment for preventing COVID-19 illness in individuals who have had sustained exposure to someone with the virus is being studied by researchers at The University of Texas Health Science Center at ...
Sep 25, 2020
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