An estimated 15 to 20 percent of all breast cancer patients are "triple negative." These unfortunate women lack three crucial treatment targets—the estrogen receptor, the progesterone receptor and human epidermal growth ...
Mar 6, 2019
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New findings put forth by the University of Maryland Fischell Department of Bioengineering (BIOE) and researchers from four other academic institutions outline a targeted therapeutic strategy to treat triple-negative breast ...
Feb 25, 2019
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47
A new "smart drug" has shown promise for women with metastatic triple-negative breast cancer, based on data from a clinical trial at NewYork-Presbyterian/Columbia's Herbert Irving Comprehensive Cancer Center and other centers. ...
Feb 20, 2019
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The MDMX and MDM2 proteins play critical roles in keeping the tumor-suppressing protein p53 from damaging the production of healthy cells. But researchers have also found a causal connection between overexpression of MDMX ...
Jan 30, 2019
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By simultaneously tackling two mechanisms for cancer's growth, an experimental therapy reduced the spread of triple-negative breast cancer in a study conducted in mice.
Jan 3, 2019
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Scientists from Cardiff University have uncovered a protein which drives aggressive breast cancer and could be targeted for developing new and improved therapies.
Dec 27, 2018
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Patients with triple-negative breast cancer who delayed starting adjuvant chemotherapy for more than 30 days after surgery were at significantly higher risk for disease recurrence and death compared with those who started ...
Dec 5, 2018
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Treating patients who had early-stage triple-negative breast cancer with the chemotherapy agent capecitabine after they completed surgery and standard chemotherapy did not significantly improve disease-free or overall survival ...
Dec 5, 2018
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A new Nature Communications study led by University of Kentucky Markey Cancer Center researchers suggests that an enzyme known as Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) is a potential therapeutic target for triple negative ...
Nov 13, 2018
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Houston Methodist scientists have developed a nanodevice to deliver immunotherapy without side effects to treat triple-negative breast cancer. Inserted straight into a tumor, this nanofluidic seed makes it possible to deliver ...
Oct 23, 2018
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