What makes triple negative breast cancer more lethal in African American women than White women or women of European descent? A new study reveals specific genetic alterations that appears to impact their prognosis and ultimately ...
Apr 22, 2015
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Combination treatment with the poly ADP-ribose polymerase (PARP) inhibitor olaparib and the investigational phosphatidylinositol-3-kinase (PI3K) inhibitor BKM120 was safe and yielded evidence of clinical benefit for women ...
Apr 22, 2015
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Early data in a preliminary human study show that an experimental immune system drug is generally safe and well tolerated in women with metastatic, triple-negative breast cancer, a persistently difficult form of the disease ...
Apr 20, 2015
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Adding the investigational agent GDC-0425, which blocks the function of a protein called checkpoint kinase 1 (Chk1), to standard doses of the chemotherapy drug gemcitabine, was safe and yielded responses in patients with ...
Apr 20, 2015
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An exhaustive analysis has been conducted of more than 12,000 distinct proteins present in an often aggressive and difficult to treat form of breast cancer, called triple-negative breast cancer.
Apr 16, 2015
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Australian researchers have found that so-called 'triple-negative breast cancers' are two distinct diseases that likely originate from different cell types. This helps explain why survival prospects for women with the diagnosis ...
Mar 27, 2015
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Scientists have revealed a brand new function for one of the first cancer genes ever discovered - the retinoblastoma gene - in a finding that could open up exciting new approaches to treatment.
Mar 26, 2015
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A University of Colorado Cancer Center study published today in the journal Molecular Cancer Therapeutics shows that only about 1 percent of triple-negative breast cancer cells in a tumor must be "androgen-receptor-positive" ...
Feb 24, 2015
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Australian researchers have identified epigenetic 'signatures' that could help clinicians tell the difference between highly aggressive and more benign forms of triple-negative breast cancer.
Feb 2, 2015
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UT Southwestern Medical Center scientists have identified a strong link between the most aggressive type of breast cancer and a gene that regulates the body's natural cellular recycling process, called autophagy.
Jan 30, 2015
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