Oncology & Cancer

A common mechanism for cancer metastasis and atherosclerosis

A key molecule for cancer metastasis has been identified as a molecule already known for its involvement in cardiovascular disease, suggesting a possible treatment approach for both diseases simultaneously.

Oncology & Cancer

How tumors make immune cells 'go bad'

Investigators from Cedars-Sinai Cancer have discovered that cancerous tumors called soft-tissue sarcomas produce a protein that switches immune cells from tumor-attacking to tumor-promoting. The study, published today in ...

Medical research

Inhibiting angiogenesis to treat cancer

Blood vessels are the body's essential architecture that exists in order to nurture cells with sufficient nutrients and oxygen. Angiogenesis, or the formation of new blood vessels, is of great research interest in cancer ...

Oncology & Cancer

Reprogrammed macrophages promote spread of breast cancer

Metastatic breast cancer cells abuse macrophages, a type of immune cell, to promote the settlement of cancer metastases in the lungs. The reprogrammed macrophages stimulate blood vessel cells to secrete a cocktail of metastasis-promoting ...

Medical research

How the cells within breast tumors communicate with each other

An article recently published in The Journal of Clinical Investigation by the group of Dr. Maria Caffarel and Miguel Servet shows for the first time that the proinflammatory cytokine Oncostatin M (OSM) favors breast cancer ...

Oncology & Cancer

Immunotherapy delays disease progression of high-grade meningiomas

Meningiomas, tumors of the membranes (meninges) surrounding the brain and spinal cord, are the most common tumors of the central nervous system. Although most meningiomas are low grade and cause few or no symptoms, a subset, ...

Oncology & Cancer

Evolution of brain tumor classification

For more than a century, pathologists have classified and graded brain tumors, examining samples under a microscope and looking for telltale signs of tumor class and biological aggressiveness such as cell morphology, cell ...

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