Medical research

'Terminator' protein halts cancer-causing cellular processes

Essential processes in mammalian cells are controlled by proteins called transcription factors. For example, the transcription factor HIF-1 is triggered by a low-oxygen situation to cause the cell to adapt to decreased oxygen.

Oncology & Cancer

Unique cells found in lung cancer patients may predict survival

Lung cancer is the leading cause of cancer-related deaths in the U.S. and most who are diagnosed with lung cancer do not survive five years. Non-small cell lung cancer (NSCLC) is the most common type where tumor cells shed ...

Oncology & Cancer

New CRISPR advance may solve key quandary

A mutation unique to certain cancer tumors is a potential homing beacon for safely deploying CRISPR gene editing enzymes to disarm DNA that makes cancer cells resistant to treatment, while ignoring the gene in normal cells ...

Oncology & Cancer

Hunting down life-threatening metastases

What makes tumor cells turn murderous? The Fraunhofer Institute for Toxicology and Experimental Medicine ITEM is investigating the mechanisms of metastasis formation—and searching for approaches for new treatments in the ...

Oncology & Cancer

Researchers identify a moving target in small cell lung tumors

Lung cancers account for approximately 25 percent of all cancer deaths. Even among those who do not smoke, 1 in 15 men and 1 in 17 women are expected to develop lung cancer in their lifetime, according to the American Cancer ...

Oncology & Cancer

Resistance to immunosurveillance favors cluster cancer metastasis

Scientific evidence suggests that cancer can metastasize to other organs when either a single cell or a cluster of cells detaches from the original tumor and travels through the blood to another location, where it grows into ...

Oncology & Cancer

Cancer cells cause inflammation to protect themselves from viruses

Researchers at the Francis Crick Institute have uncovered how cancer cells protect themselves from viruses that are harmful to tumors but not to healthy cells. These findings could lead to improved viral treatments for the ...

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Tumor

A tumor or tumour is the name for a swelling or lesion formed by an abnormal growth of cells (termed neoplastic). Tumor is not synonymous with cancer. A tumor can be benign, pre-malignant or malignant, whereas cancer is by definition malignant.

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