Most of the roughly 40 trillion cells of your body have nearly identical copies of your genome—the DNA inherited from your parents, containing instructions for everything from converting food to energy to fighting off infections. ...
May 27, 2022
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People with neurofibromatosis type 1 (NF1) develop tumors on nerves throughout their bodies. These tumors are usually benign—meaning they don't spread to other parts of the body and are not considered life-threatening—but ...
May 19, 2022
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New findings from researchers at Memorial Sloan Kettering Cancer Center (MSK) and published today in the journal Nature Communications report the results of using a comprehensive sequencing approach on 114 pediatric, adolescent, ...
May 18, 2022
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Though the mutations accumulated by cancer cells occur more or less randomly, certain regions of genes essential to cancer growth appear to be more frequently mutated than others in established tumors. Now, a study led by ...
May 11, 2022
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Inhibitors of the protein EZH2 are effective against cancers with SMARCB1 mutations such as rhabdoid tumors in children. However, these drugs are subject to treatment resistance. Scientists at St. Jude Children's Research ...
May 9, 2022
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By introducing cancer-causing mutations into healthy skin cells step-by-step, Broad scientists have created models of skin cancer that can reveal the effects of mutations.
Apr 29, 2022
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About one-fifth of often deadly head and neck cancers harbor genetic mutations in a pathway that is key to normal cell growth, and scientists report those mutations, which enable abnormal cancer cell growth, can also make ...
Apr 28, 2022
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A mutated gene found in more than 20% to 30% of breast cancer recurrences may help tumors become more aggressive and promote metastasis, according to a pair of new studies that uncover mechanisms behind these processes and ...
Apr 19, 2022
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Cancer therapies targeting specific genetic mutations may offer benefits to patients for whom other standard chemotherapy treatments have not effectively treated their tumor. However, genetic screening of tumors is not routinely ...
Apr 5, 2022
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A team led by researchers at Broad Institute of MIT and Harvard, Dana-Farber Cancer Institute, and Harvard Medical School has developed a new method to identify thousands of DNA mutations accurately and efficiently in a patient's ...
Mar 18, 2022
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