The genome of the most common form of ovarian cancer is characterized by a few common gene mutations but also surprisingly frequent structural changes in the genome itself, said members of The Cancer Genome Atlas, including ...
Jun 29, 2011
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Research led by the Cancer Biology Laboratory of the Department of Medicine and Life Sciences (MELIS) at Pompeu Fabra University, in collaboration with the Center for Genomic Regulation and the Murcian Institute of Biosanitary ...
Jul 8, 2024
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Tumor protein P53 (TP53) plays an important role in suppressing the growth of tumors. Mutations in the gene for TP53 can have a disastrous effect, hampering the body's ability to fight tumors and even encouraging their growth. ...
May 30, 2024
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Ultrasound imaging offers a valuable and noninvasive way to find and monitor cancerous tumors. However, much of the most crucial information about a cancer, such as specific cell types and mutations, cannot be learned from ...
May 13, 2024
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A genetic test that identifies cancer mutations in solid tumors and that was developed by researchers at Washington University School of Medicine in St. Louis has been approved for reimbursement by the Centers for Medicare ...
Feb 26, 2024
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Epithelioid sarcoma, a rare aggressive cancer that usually strikes young adults, and rhabdoid tumors, which affect children, have long been difficult to treat. But the outlook for people with these subtypes of soft tissue ...
Feb 5, 2024
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Researchers at the University of Tsukuba have demonstrated that in T follicular helper cell lymphoma, a subgroup of hematologic malignancies, individual tumor cells are highly heterogeneous, even within the same patient.
Dec 5, 2023
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Researchers at Kanazawa University report in Cancer Research how Kras and p53 mutations influence the tumor suppressor and promoter functions of a TGF- ß pathway. The findings may lead to a new approach for colorectal cancer ...
Nov 29, 2023
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The p53 protein is a tumor suppressor that plays a crucial role in preventing the formation of cancerous cells. But when it mutates and becomes defective in cells, the protein can significantly boost a person's risk of cancer ...
Nov 28, 2023
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A new editorial perspective titled "Genetic modifiers of p53: opportunities for breast cancer therapies" has been published in Oncotarget.
Oct 25, 2023
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