It has been estimated that more than 80 million people in the world have an unfulfilled desire to have children. But for every 10th couple, the reasons therefor remain unclear. Now, researchers from the Leibniz Institute ...
Mar 28, 2017
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Investigators at the Massachusetts General Hospital (MGH) Cancer Center have identified the first genetic mechanisms conferring acquired resistance to a promising group of targeted cancer drugs. In a paper appearing in the ...
Mar 23, 2017
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Casting one of the largest genomic nets to date for the rare tumors of the autonomic nervous system known as pheochromocytoma and paraganglioma (PCC/PGL) captured several new mutations driving the disease that could serve ...
Feb 13, 2017
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Tumors of the elderly, such as breast cancer and colon cancer, accumulate thousands of DNA mutations. These genetic defects contribute to cancer-specific properties including uncontrolled growth, invasion in neighboring tissues, ...
Jan 30, 2017
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In recent years, researchers have identified specific gene mutations linked to gastrointestinal stromal tumors (GIST), which primarily occur in the stomach or small intestine, with 5,000 to 6,000 new cases per year in the ...
Dec 15, 2016
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Next-generation sequencing for patients at UCSF Medical Center is prompting changes in brain tumor diagnoses for some children and a retooling of treatment plans in many cases. Sequencing is also providing valuable insights ...
Nov 16, 2016
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The cause of a rare and highly aggressive form of non-Hodgkin lymphoma that attacks the face has been discovered by an international genome-scanning research project.
Nov 16, 2016
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Melanoma tumors use genetic mutations in a prominent immune response pathway to resist the immunotherapy ipilimumab, researchers from The University of Texas MD Anderson Cancer Center report in the journal Cell.
Sep 22, 2016
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In the late 1990s, University of Kentucky Professor Douglas Andres found that mutations in a protein known as RIT1 could initiate cancer development in laboratory models.
Aug 17, 2016
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A newly defined type of colorectal and endometrial cancer involves at least two somatic mutations in the mismatch repair genes (MMR): MLH1, MSH2, MSH6, PMS2. This double somatic MMR cancer has no germline mutations in the ...
Aug 16, 2016
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