A collaborative experimental study led by researchers at Cima and Clinica Universidad de Navarra proposes a new therapeutic approach against cancer that dissociates efficacy and toxicity in the use of combined immunotherapy ...
May 3, 2019
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197
A team of researchers from the Netherlands, the U.S. and the U.K. has found evidence that suggests tumor necrosis factor (TNF) cannot be used as a biomarker for rheumatoid arthritis (RA) treatment discontinuation. In their ...
Spondyloarthritis is one of the most common types of chronic joint inflammation, affecting nearly 1 to 2 percent of the Western population. Cytokine blockade of tumor necrosis factor (TNF), and more recently, Interleukin-17 ...
Jan 11, 2019
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209
Scientists at Scripps Research have discovered the role of an immune system double agent. This molecule, called USP18, can help curtail immune responses, but it can also open the door to bacterial infections, such as harmful ...
Oct 4, 2018
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133
Oxidative stress can help tumors thrive, but one way novel cancer treatments work is by pushing levels to the point where it instead helps them die, scientists report.
Jun 21, 2018
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139
Aggressive cancers like glioblastoma and metastatic breast cancer have in common a siren call that beckons the bone marrow to send along whatever the tumors need to survive and thrive.
Jan 23, 2018
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992
Superficially, psoriasis and atopic dermatitis may appear similar but their commonalities are only skin deep. Atopic dermatitis, also known as eczema, is primarily driven by an allergic reaction, while psoriasis is considered ...
May 22, 2017
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128
Immunotherapy with T-cells offers great hope to people suffering from cancer. Some initial successes have already been made in treating blood cancer, but treating solid tumors remains a major challenge. The signaling molecule ...
Apr 26, 2017
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118
Investigators at the Ted Rogers Centre for Heart Research have discovered a surprising new role for tumor necrosis factor (TNF): namely, that it is a major regulator of small blood vessel function, the key determinant of ...
Apr 6, 2017
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138
Twenty years ago, tumor necrosis factor (TNF) seemed a promising target in the treatment of brain diseases like multiple sclerosis or Alzheimer's Disease. But clinical trials produced disappointing results. Now University ...
Oct 10, 2016
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