A modified protein in benign-appearing meningiomas can reveal which are truly benign and which are more dangerous and require more aggressive treatment, researchers have discovered.
Nov 5, 2019
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Immunotherapy has become a standard treatment approach for several types of cancer, including melanoma. However, tumors can escape immune cell detection even with the use of immunotherapies. In a new study published in Cancer ...
Nov 1, 2019
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A team of researchers affiliated with several institutions in the U.S. and Australia (and sponsored by pharmaceutical company Amgen Research) has found that a drug they optimized to target a protein produced due to mutations ...
Most cancers kill because tumor cells spread beyond the primary site to invade other organs. Now, a USC study of brain-invading breast cancer cells circulating in the blood reveals they have a molecular signature indicating ...
Oct 22, 2019
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As tumor cells multiply, they often spawn tens of thousands of genetic mutations. Figuring out which ones are the most promising to target with immunotherapy is like finding a few needles in a haystack. Now a new model developed ...
Oct 9, 2019
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A novel anticancer molecule created by researchers at The Wistar Institute showed therapeutic activity in preclinical models of various cancer types. This cell-permeable peptidomimetic was designed to disrupt a newly identified ...
Oct 3, 2019
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A recent study in The FASEB Journal identifies a new mechanism of pancreatic tumors' resistance to chemotherapeutic treatment. The mechanism involves the loss of function of promyelocytic leukemia protein (PML), which operates ...
Sep 26, 2019
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Lack of oxygen, or hypoxia, is a biological stressor that occurs under various conditions such as wound healing and stroke. To rescue the tissue, the body has innate mechanisms that "kick in" to make the cells of the hypoxic ...
Sep 19, 2019
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Biomedical engineers at Duke University have developed a method to address failures in a promising anti-cancer drug, bringing together tools from genome engineering, protein engineering and biomaterials science to improve ...
Sep 16, 2019
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Researchers at the Johns Hopkins Kimmel Cancer Center discovered that a cell adhesion protein, E-cadherin, allows breast cancer cells to survive as they travel through the body and form new tumors, a process termed metastasis. ...
Sep 10, 2019
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